Table 7.
Number of cases with persistent disease/total number (%) in each ATA and TNM stage categorized by the presence and type of mutation.
| Stage | No mutations No. (%) |
BRAF only
No. (%) |
TERT only
No. (%) |
BRAF/TERT
No. (%) |
Total |
|---|---|---|---|---|---|
| ATA stages | P <0.0001 | ||||
| Low | 5/39 (12.8) | 9/35 (25.7) | 3/15 (20) | 2/7 (28.6) | 19/96 (19.8) |
| Intermediate | 16/50 (32.0) | 20/53 (37.7) | 4/11 (36.4) | 8/11 (72.7) | 48/125 (38.4) |
| High | 18/32 (56.2) | 8/15 (53.3) | 12/12 (100) | 16/16 (100) | 54/75 (72.0) |
| TNM stage | P <0.0001 | ||||
| I | 14/39 (26.4) | 16/43 (37.0) | 1/2 (50.0) | 0/1 (0) | 31/99 (31.3) |
| II | 15/53 (28.5) | 16/35 (31.4) | 7/24 (29.2) | 15/22 (68.5) | 53/150 (35.3) |
| III | 7/12 (58.3) | 4/7 (57.1) | 5/6 (83.3) | 2/2 (100) | 18/27 (66.7) |
| IV | 3/3 (100) | 1/2 (50.0) | 6/6 (100) | 9/9 (100) | 19/20 (95) |