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. 2023 Oct 17;330(15):1459–1471. doi: 10.1001/jama.2023.18497

Figure 2. Treatment Assignment and Outcomes in Strata of Orthostatic Hypotension for Cardiovascular Disease or All-Cause Mortality and All-Cause Mortality by Trial.

Figure 2.

HR indicates hazard ratio; NA, not applicable (not calculable). The HRs in strata of orthostatic hypotension are pooled by trial type (trial of blood pressure [BP] goal or placebo-controlled trial) and overall. Point estimates (circles) were generated with Cox models adjusted for age and sex. Pooled estimates (diamonds) were also adjusted for study. Point estimate sizes are weighted by number of participants as a proportion of the total in the pooled population. Whiskers represent 95% CIs. P values for interaction are comparisons of point estimates across strata. Orthostatic hypotension is defined as a change in systolic BP on standing of −20 mm Hg or more extreme or diastolic BP of −10 mm Hg or more extreme. Corresponding numbers are available in eTable 14 in Supplement 1.

aP = .04.