Skip to main content
. 2023 Oct 17;330(15):1459–1471. doi: 10.1001/jama.2023.18497

Figure 3. Treatment Assignment and Outcomes in Strata of Standing Hypotension for Cardiovascular Disease or All-Cause Mortality and All-Cause Mortality by Trial.

Figure 3.

HR indicates hazard ratio; NA, not applicable (not calculable). The HRs in strata of standing are pooled by trial type (trial of blood pressure [BP] goal or placebo-controlled trial) and overall. Trial point estimates (circles) were generated with Cox models, with adjustment for age and sex. Pooled estimates (diamonds) were also adjusted for study. Point estimate sizes are weighted by number of participants as a proportion of the total number in the pooled population. Whiskers represent 95% CIs. P values for interaction are comparisons of point estimates across strata. Standing hypotension is defined as a systolic BP of ≤110 mm Hg or a diastolic BP of ≤60 mm Hg. Corresponding numbers are available in eTable 15 in Supplement 1.