Figure 4.

p2rx4 deletion does not affect microglial morphology in the dorsal horn of the spinal cord

(A) Representative images of Iba1 staining in the ipsilateral and contralateral dorsal of the spinal cord from sham and SNI male and female mice. Scale bars: 200 μm.

(B) Quantification of the area covered by microglia from A. A significant increase of the Iba1 area was observed in the ipsilateral side of the DH from the three genotypes. Data are represented as mean ± SEM. N = 3 mice per group. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.005, ∗∗∗∗p < 0.001, two-way ANOVA.