TABLE 1.
Correlation between the IC50 of lumefantrine and those of other antimalarial drugs
| Drug 1 | Drug 2 | na | rb | Pc |
|---|---|---|---|---|
| Lumefantrine | Chloroquine | 38 | −0.187 | NS |
| Lumefantrine | Monodesethylamodiaquine | 40 | −0.036 | NS |
| Lumefantrine | Quinine | 54 | 0.135 | NS |
| Lumefantrine | Mefloquine | 32 | 0.688 | <0.01 |
| Lumefantrine | Halofantrine | 61 | 0.677 | <0.01 |
| Lumefantrine | Artesunate | 61 | 0.420 | <0.01 |
| Lumefantrine | Pyrimethamine | 44 | −0.013 | NS |
n, number of paired results.
Correlation coefficient (r) was calculated from linear regression analysis of logarithmic IC50.
Probability (P) refers to the significance level of the test (P < 0.05). NS, nonsignificant.