Figure 2. Decay of intact proviruses after ART initiation.
Frequency of intact proviruses during (A) the first 6 months of ART or (B) over the first 4 years of treatment. Datapoints represent the geometric mean from at least 3 replicates per animal. Open circles indicate that no positive events were detected by the IPDA; the y-axis value indicates the limit of detection based on the number of cell equivalents assayed. (C) Decay of intact proviruses in individual animals during ART. Data were fitted to a triphasic model (black line) as described in the Methods. Vertical lines indicate the standard deviations.