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Double-disk synergy test with the transformant E. coli JM101(pSAL2-ind). (A) Synergy test with 10 μg of clavulanate (disk 6); (B) synergy test with 20 μg of RO48-1220 (disk 7). Disks: 1, cefotaxime; 2, ceftazidime; 3, moxalactam; 4, cefotetan; 5, aztreonam.