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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: Am J Med Genet C Semin Med Genet. 2023 Apr 18;196(1):e32041. doi: 10.1002/ajmg.c.32041

Table 3.

Caregiver concerns for the adults with Down syndrome they care for, stratified by age of the individual with Down syndrome

Age of person with Down syndrome
Total 18–29 years 30–45 years 46+ years
N=438 N=208 N=160 N=70
N % N % N % P-Value N % P-Value
Home modifications/safety 55 12.6 24 11.5 13 8.1 0.08 16 22.9 <0.01
Future residential options 272 62.1 128 61.5 90 56.3 <0.01 39 55.7 <0.01
Physical health 236 53.9 107 51.4 86 53.8 0.5 43 61.4 0.09
Mental health 191 43.6 96 46.2 63 39.4 0.02 27 38.6 0.03
Alzheimer’s disease /Dementia 232 53.0 88 42.3 81 50.6 <0.01 47 67.1 <0.01
Guardianship/legal options 107 24.4 60 28.8 30 18.8 0.02 17 24.3 0.5
Employment/employment alternatives 277 63.2 108 51.9 47 29.4 0.1 2 2.9 0.3
Financial security 170 38.8 106 51.0 50 31.3 <0.01 14 20.0 <0.01
Adult education opportunities 91 20.8 61 29.3 26 16.3 <0.01 2 2.9 0.1
Friendships/relationships 277 63.2 148 71.2 107 66.9 0.5 22 31.4 <0.01
Safety and neglect 168 38.4 97 46.6 54 33.8 0.02 17 24.3 <0.01
Transportation support 133 30.4 82 39.4 43 26.9 0.03 8 11.4 <0.01

Bold indicates statistical significance at alpha=0.05

For age comparisons, 18–29 years is the referent group

P values calculated using logistic regression modeling the effect of age on caregiver concern, adjusted for caregiver education.