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Global A-to-I editing in Alu elements. (A) The Alu editing index (AEI) in nasal swabs of COVID-19 patients is significantly elevated compared to controls. (B) The high index of A-to-G mismatch, compared to any other possible mismatch, is indicative to the cleanness of the A-to-I editing signal. (C) The Alu editing index (AEI) is significantly elevated in COVID-19 compared to controls, in 4 different datasets of whole blood, leukocytes and nasal-swabs.
