Table 4.
Threshold effect analysis of TyG index on all-cause and CVD mortality in CVD patients with diabetes or pre-diabetes
| Adjusted HR (95% CI), P-value | |
|---|---|
| All-cause mortality | |
| Total | 1.12(0.92,1.35) 0.25 |
| Fitting by two-piecewise Cox proportional risk model | |
| Inflection point | 9.05 |
| TyG index < 9.05 | 0.47(0.27,0.81) 0.01 |
| TyG index ≥ 9.05 | 1.42(1.02,1.99) 0.04 |
| P for Log-likelihood ratio | < 0.001 |
| CVD mortality | |
| Total | 1.53(1.08,2.18) 0.02 |
| Fitting by two-piecewise Cox proportional risk model | |
| Inflection point | 8.84 |
| TyG index < 8.84 | 0.25(0.07,0.89) 0.03 |
| TyG index ≥ 8.84 | 1.77(1.08,2.91) 0.02 |
| P for Log-likelihood ratio | < 0.001 |
Cox proportional hazards models were used to estimate HR and 95% CI. Adjusted for age, gender, race, BMI, tobacco use, alcohol use, education, hypertension, COPD, family income-poverty ratio. HR: Hazard ratio; CI: Confidence interval