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. 2023 Oct 18;21:379. doi: 10.1186/s12951-023-02150-4

Fig. 6.

Fig. 6

Antidepressant effects of BDNF-Quercetin nanogels on the CUMS rats. (a) Schematic diagram of the CUMS procedure. (b) Changes in body weight of rats. (c) Changes of 1% sucrose preference of rats. (d) Number of rearings. (e) Total distance of rats. (f) BDNF concentration in plasma. (g) BDNF content in the hippocampus. (h) IL-6 concentration in plasma. (i) PGE2 content in the hippocampus. ##p < 0.01 compared with the control group. *p < 0.05, **p < 0.01 compared with CUMS model. @p < 0.01 compared with the fluoxetine