TABLE 3.

PAEs and PA-SMEs of ceftriaxone^a

Strain	PAE (h)	PA-SME (h) of ceftriaxone at the following multiples of the MIC:
		0.1×	0.2×	0.3×	0.4×	0.5×
S. aureus ATCC 29231	0.9 (0.7–1.0)	3.0 (2.7–3.3)	4.8 (4.1–5.6)	7.2 (6.1–8.5)	(>15.9–>16.1)	(>15.9–>16.1)
S. pneumoniae ATCC 6306	2.6 (2.3–2.9)	2.9 (2.6–3.3)	4.2 (3.7–4.9)	6.2 (5.7–6.7)	(>14.3–>15)	(>14.3–>15)
H. influenzae NTCC 8468	−0.8 (−0.6–−1.0)	−0.6 (−0.3–−1.0)	−0.4 (−0.3–−0.6)	−0.3 (−0.3)	0.4 (−0.3–−1.0)	3.8 (0.6–4.4)
E. coli ATCC 25922	−2.1 (−2.0–−2.1)	−2.1 (−2.0–−2.1)	−1.9 (−1.7–−2.1)	−1.6 (−1.2–−2.1)	−1.3 (−0.7–−1.6)	7.1 (5.3–8.3)

^aValues are means (ranges).