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. 2023 Oct 17;21:732. doi: 10.1186/s12967-023-04581-x

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — LINC02913 expression affected ADSC cell phenotype under hypoxia and normoxia. A LINC02913 expression in ADSCs cells treated with different oxygen extensions was detected using qRT-PCR; B the transfection efficiency of LINC02913 overexpression plasmid (LINC02913 OE) was verified using qRT-PCR; C the changes in cell viability after LINC02913 overexpression under hypoxia and normoxic conditions were detected using CCK-8 assay; D the changes in the adipogenic ability of cells after LINC02913 overexpression under hypoxia and normoxic conditions were detected using oil red O staining; E after the induction for endothelial differentiation of ADSCs, cell tube formation after LINC02913 overexpression under hypoxia and normoxic conditions were detected using the tube formation assay; F the expression of endothelial cell marker CD31 was detected using IF staining after LINC02913 overexpression under hypoxia and normoxic conditions; G the level of endothelial cell markers (CD133, CD31, VEGFA, and eNOS) after LINC02913 overexpression under hypoxia and normoxic conditions was detected using western blot. **p < 0.01 compared to Nypoxia + vector group; ##p < 0.01, compared with Hypoxia+vector group