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. 2023 Sep 25;14(16):3151–3168. doi: 10.7150/jca.88485

Figure 3.

Figure 3

The development and verification of a pyroptosis-related signature. (A) The distribution of lambda values in LASSO analysis. (B) Coefficient distribution of LASSO regression analysis of 34 prognosis-related lncRNAs. (C) Plot of risk score (top), survival status (middle), and RNA expression heatmap (below) of patients in the training cohort. In the risk score graph, the risk scores of the low- and high- risk group are represented by the green and red curve, respectively. The green and red dots in the survival state diagram indicate the samples whose survival state is alive and dead, respectively. In the RNA expression heatmap, red and green indicates the up and down regulation of the lncRNA in the sample, respectively. (D) Kaplan-Meier survival analysis of high- and low-risk patients in the training cohort. (E) ROC curve for assessing the efficacy of our signature in predicting patients' 1-year, 3-year, 5-year, and 10-year survival rates in the training cohort. (F) Plot of risk score (top), survival status (middle), and RNA expression heatmap (below) of patients in the testing cohort. (G) Kaplan-Meier survival analysis of high- and low-risk patients in the testing cohort. (H) ROC curve for assessing the efficacy of our signature in predicting patients' 1-year, 3-year, 5-year, and 10-year survival rates in the testing cohort. LASSO: The Least Absolute Shrinkage and Selectionator operator, lncRNAs: Long non-coding RNAs, ROC: receiver operating characteristic curve.