Table 1:
Baseline characteristics of participants overall and by primaquine dose group
Overall (n=81) | Control group (0 mg/kg; n=16) |
0·0625 mg/kg group (n=16) |
0·125 mg/kg group (n=17) |
0·25 mg/kg group (n=15) |
0·5 mg/kg group (n=17) |
|
---|---|---|---|---|---|---|
Age (years) | 12 (7–25) | 22 (7–30) | 10 (8–11) | 22 (7–32) | 10 (7–16) | 18 (8–30) |
Haemoglobin (g/L) | 124 (112–138) | 130 (110–139) | 120 (108–129) | 135 (111–144) | 119 (112–132) | 122 (113–142) |
Gametocyte density by microscopy (per μL) | 64 (32–720) | 64 (32–144) | 96 (48–576) | 80 (32–320) | 144 (48–720) | 48 (32–192) |
Asexual parasite prevalence by microscopy | 54 (67%) | 8 (50%) | 11 (69%) | 14 (82%) | 8 (53%) | 13 (77%) |
Asexual parasite density by microscopy (per μL)* | 376 (64–2128) | 176 (40–3840) | 1088 (144–2832) | 216 (48–1264) | 1656 (432–9808) | 144 (32–1792) |
Symptomatic malaria† | 6 (7%) | 0 | 3 (19%) | 1 (6%) | 0 | 2 (12%) |
Data are median (IQR) or n (%). * Median parasite densities were calculated for parasite-positive individuals only. † Temperature ≥37·5°C and parasitaemic.