Table 2:

Average within-person percentage reduction in mosquito infectivity at day 1, 2, and 7 after treatment

	Reduction at day 1	Reduction at day 2	Reduction at day 7
Population assessed for infectivity (n=71)
Control group	16·2% (14·7 to 46·9); ref	11·3% (−27·4 to 50·0); ref	45·8% (11·9 to 82·2); ref
0·0625 mg/kg group	38·2% (7·4 to 68·9); p=0·17	41·9% (1·4 to 82·5); p=0·16	77·9% (55·1 to 100); p=0·050
0·125 mg/kg group	37·9% (−6·7 to 82·6); p=0·19	54·9% (13·4 to 96·3); p=0·096	66·7% (35·4 to 97·9); p=0·25
0·25 mg/kg group	80·9% (59·4 to 100); p=0·0036	92·6% (78·3 to 100); p=0·0014	93·3% (79·0 to 100); p=0·0099
0·5 mg/kg group	78·5% (54·0 to 100); p=0·0040	75·0% (45·7 to 100); p=0·014	81·5% (59·6 to 100); p=0·049
Participants who were infectious before treatment (n=57)
Control group	22·6% (−22·4 to 67·6); ref	27·5% (−22·7 to 77·7); ref	66·1% (22·7 to 100); ref
0·0625 mg/kg group	47·0% (10·2 to 83·6); p=0·18	59·3% (16·9 to 100); p=0·18	97·4% (91·7 to 100); p=0·052
0·125 mg/kg group	69·4% (21·4 to 100); p=0·057	94·9% (84·6 to 100); p=0·045	100% (100 to 100); p=0·142
0·25 mg/kg group	87·8% (70·4 to 100); p=0·014	99·2% (97·6 to 100); p=0·0082	100% (100 to 100); p=0·052
0·5 mg/kg group	91·5% (73·4 to 100); p=0·0064	87·6% (60·2 to 100); p=0·030	95·1% (84·2 to 100); p=0·11

Data are mean (95% CI), unless stated otherwise. Reduction in infectivity measured as the average change in proportion of dissected mosquitoes with oocysts.