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. 2023 Oct 4;10:1089087. doi: 10.3389/fmed.2023.1089087

Table 3.

Comparison of patients in automated versus manual reviews and measures of agreement for individual responses for categorical (nominal) variables.

Variable name Percent agreement, automated vs. manual Sensitivity Specificity Kappa coefficient (95% CI, SE) Strength of agreement based on Kappa coefficient
Sex, N = 652 99.7 99.7 0.99 (0.99–1.0, 0) Almost perfect
Male 359/360 (99.7)
Female 291/292 (99.7)
Total 650/652 (99.7)
Coronary artery disease, N = 540 98.6 97.4 0.90 (0.85–0.96, 0.03) Almost perfect
Yes 73/74 (98.6)
No 454/466 (97.4)
Total 527/540 (97.6)
Hypertension, N = 540 92.0 93.5 0.85 (0.80–0.89, 0.02) Almost perfect
Yes 298/324 (92.0)
No 202/216 (93.5)
Total 500/540 (92.6)
Congestive heart failure, N = 540 88.0 97.8 0.82 (0.74–0.90, 0.04) Almost perfect
Yes 44/50 (88)
No 479/490 (97.8)
Total 523/540 (96.7)
Chronic obstructive pulmonary disease, N = 540 92.7 96.3 0.80 (0.72–0.88, 0.04) Substantial
Yes 51/55 (92.7)
No 467/485 (96.3)
Total 518/540 (95.9)
Asthma, N = 540 93.7 95.8 0.81 (0.73–0.88, 0.04) Almost perfect
Yes 59/63 (93.7)
No 457/477 (95.8)
Total 516/540 (95.6)
Chronic kidney disease, N = 540 81.2 96.2 0.79 (0.72–0.85, 0.03) Substantial
Yes 95/117 (81.2)
No 407/423 (96.2)
Total 502/540 (93)
Diabetes mellitus, N = 540 92.1 96.3 0.89 (0.85–0.93, 0.02) Almost perfect
Yes 176/191 (92.1)
No 336/349 (96.3)
Total 512/540 (94.8)
Dyslipidemia/Hyperlipidemia, N = 540 88.9 86.4 0.61 (0.53–0.69, 0.04) Substantial
Yes 80/90 (88.9)
No 389/450 (86.4)
Total 469/540 (86.9)
ICU admission rate, N = 611 90.3 95.2 0.86 (0.82–0.90, 0.02) Almost perfect
Yes 215/238 (90.3)
No 355/373 (95.2)
Total 570/611 (93.3)
IMV rate, N = 582 87.7 98 0.85 (0.79–0.92, 0.03) Almost perfect
Yes 64/73 (87.7)
No 499/509 (98)
Total 563/582 (96.7)
NIMV rate, N = 581 83.3 99.3 0.80 (0.66–0.95, 0.07) Substantial
Yes 15/18 (83.3)
No 559/563 (99.3)
Total 574/581 (98.3)
HFNC rate, N = 581 100 98.9 0.86 (0.75–0.97, 0.06) Almost perfect
Yes 19/19 (100)
No 556/562 (98.9)
Total 575/581 (99)
ECMO rate, N = 581 72.7 99.3 0.69 (0.47–0.91, 0.11) Substantial
Yes 8/11 (72.7)
No 566/570 (99.3)
Total 574/581 (98.8)
ICU discharge status, N = 172 100 100 1.0 (1–1, 0.0) Almost perfect
Death 9/9 (100)
Alive 163/163 (100)
Total 172/172 (100)
Hospital discharge status, N = 541 90 100 0.94 (0.88–1, 0.03) Almost perfect
Death 27/30 (90)
Alive 511/511 (100)
Total 538/541 (99.4)

CI, Confidence interval; ECMO, Extracorporeal membrane oxygenation; HFNC, High Flow Nasal Canula; ICU, Intensive Care Unit; IMV, Invasive Mechanical Ventilation; LOS, Length of stay; NIMV; Non-Invasive Mechanical Ventilation; PCC, Pearson Interclass Correlation Coefficient; SE, Standard Error.