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. 2023 Sep 8;67(10):e00534-23. doi: 10.1128/aac.00534-23

TABLE 1.

Effectiveness of all sanitizers against eight strains of C. parapsilosis and S. aureus in monospecies and mixed biofilms a

Recommended use Active constituent/use concentration Exposure time C. parapsilosis biofilms S. aureus biofilm Mixed biofilms
Topical use CLX 2.0% 1 min E E E
CLX 0.5% 3 min E E E
PVP-I 10% 3 min E E E
Environment surfaces NaClO 0.02% 60 min I I I
NaClO 1% 30 min I I I
ADBAC 0.32% 10 min I I I
H2O2 (4.25%) + DDAC (5.6%) pure 10 min I b b
H2O2 (4.25%) + DDAC (5.6%) 1:25 10 min I b b
PMS 1% 10 min I I I
ADBAC (0.08%) + ABAC (0.02%) pure 3 min E E E
ADBAC (0.08%) + ABAC (0.02%) 1:20 6 min E E E
Sterilization of non-autoclavable medical devices PAA (3.5%) + H2O2 (2.6%) 0.1% 3 min E b b
PAA (3.5%) + H2O2 (2.6%) 0.2% 10 min E b b
GLA 2% 30 min E E E
OPA 0.55% 10 min E E E
a

ADBAC, alkyl dimethyl benzyl ammonium chloride; ABAC, alkyl benzyl ammonium chloride; CLX, chlorhexidine gluconate; GLA, glutaraldehyde; DDAC, didecyl dimethyl ammonium chloride; H2O2, hydrogen peroxide; PAA, peracetic acid; NaClO, sodium hypochlorite; OPA, D-orthophthalaldehyde; PMS, potassium monopersulfate; PVP-I, polyvinyl pyrrolidone; I, ineffective; E, effective; min, minutes.

b

Impaired result due to high catalase activity of the S. aureus.