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. 2023 Sep 8;67(10):e00534-23. doi: 10.1128/aac.00534-23

TABLE 2.

Logarithmic decreases and resulting antimicrobial activity in monospecies and mixed biofilms of C. parapsilosis and S. aureus strains after using the four selected sanitizers.

Treatment Log10 CFU/mL ± SD a
obtained after exposure
Reduction factor Antimicrobial activity
S. aureus C. parapsilosis S. aureus C. parapsilosis S. aureus C. parapsilosis
Monospecies biofilms
 CLX b (0.5%) 1.14 ± 0.23 0.67 ± 0.08 8.03 9.1 Bactericidal g Fungicidal g
 PVP-I c (10%) 4.75 ± 0.04 1.59 ± 0.37 4.42 8.18 Bactericidal Fungicidal
 ADBAC d (0.08%) with ABAC e (0.02%) 6.48 ± 0.15 1.69 ± 0.03 2.69 8.08 Bacteriostatic Fungicidal
 OPA f (0.55%) 5.90 ± 0.59 0.53 ± 0.13 3.27 8.94 Bacteriostatic Fungicidal
Mixed biofilms
 CLX a (0.5%) 0.60 ± 0.11 1.25 ± 0.02 7.12 5.35 Bactericidal Fungicidal
 PVP-I b (10%) 3.55 ± 0.02 2.56 ± 0.01 4.17 4.04 Bactericidal Fungicidal
 ADBAC c (0.08%) plus ABAC e (0.02%) 5.52 ± 0.02 2.21 ± 0.03 2.20 4.39 Bacteriostatic Fungicidal
 OPA f (0.55%) 4.48 ± 0.11 2.55 ± 0.09 3.24 4.05 Bacteriostatic Fungicidal
a

SD, standard deviation.

b

CLX, chlorhexidine gluconate.

c

PVP-I, polyvinyl pyrrolidone.

d

ADBAC, alkyl dimethyl benzyl ammonium chloride.

e

ABAC, alkyl benzyl ammonium chloride.

f

OPA, D-orthophthalaldehyde.

g

Adopted criterion BS EN 13697:2015 + A1:2019.