Table 3.
Associations between exposure to prenatal EDC mixture and BMI trajectories from BWQS regression expressed as ORs (95% CrIs) using imputed data (), given unstratified and stratified by sex and socioeconomic status; for the INMA birth cohort study.
Models | Class 1: higher birth size with accelerated BMI gain | Class 2: higher birth size with slower BMI gain | Class 3: lower birth size with accelerated BMI gain | Class 4: average birth size with slower BMI gain | Class 5: lower birth size with slower BMI gain |
---|---|---|---|---|---|
Unstratifieda | 1.15 (0.68, 1.97) | 1.16 (0.86, 1.58) | 1.70 (1.03, 2.61) | Ref | 1.23 (0.83, 1.88) |
Sexb | |||||
Female | 1.38 (0.61, 3.10) | 1.57 (1.03, 2.41) | 1.43 (0.81, 2.59) | Ref | 1.32 (0.76, 2.32) |
Male | 1.11 (0.61, 2.08) | 0.79 (0.50, 1.25) | 1.84 (0.88, 3.71) | Ref | 1.08 (0.63, 1.92) |
SESc | |||||
High | 1.68 (0.66, 4.31) | 1.02 (0.63, 1.72) | 1.05 (0.49, 1.44) | Ref | 1.23 (0.63, 2.44) |
Middle | 0.68 (0.26, 1.97) | 1.39 (0.61, 2.23) | 1.09 (0.47, 2.72) | Ref | 0.90 (0.38, 2.08) |
Low | 1.25 (0.67, 2.41) | 1.38 (0.86, 2.27) | 2.32 (1.28, 4.44) | Ref | 1.42 (0.73, 2.72) |
Note: Using data from the first imputed data set. BMI, body mass index; BWQS, Bayesian weighted quantile sum; CrI, credible interval; EDC, endocrine-disrupting chemical; INMA, INfancia y Medio Ambiente; N, number of observations; OR, odds ratio; Ref, reference; SES, socioeconomic status.
Unstratified models adjusted for child sex, parity, SES, maternal and paternal BMI, maternal smoking, maternal age, Mediterranean diet score, and subcohort.
Sex-stratified models adjusted for the same as unstratified models with the exception of sex.
SES-stratified models adjusted for the same as unstratified models with the exception of SES.