Table 5.

Candidate SNP markers associated with the malignancy grade of MGT derived from the linear regression test.

Marker	Chromosome	Position	Gene	Variant	Allele (M > m)	MAF	Major Homo (mean)	Hetero (mean)	Minor Homo (mean)	P value†	R value†	P value‡	Slope‡
BICF2S23436248	34	22,547,748	IL1RAP	Exon	A > G	0.385	9(2.00)	8(1.13)	4(0.00)	0.002	0.574	0.0002	−1.088
BICF2P605684	8	70,488,402	MOK	Exon	G > A	0.219	14(0.71)	5(2.40)	2(2.50)	0.003	0.558	0.0002	1.212

SNP, single-nucleotide polymorphism; MGT, mammary gland tumor; M > m, major allele to minor allele; MAF, minor allele frequency. ^†Correlation/trend; ^‡Linear regression. (Genome-wide significance level: α′ = 3.94×10⁻⁷).