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. 2023 Aug 17;14(10):2068–2078. doi: 10.1039/d3md00306j

Inhibitory activity against SARS-CoV-2 3CLpro.

Compounds D1N8 D1N18 D1N52 L-26
IC50a (μM) 0.44 ± 0.12 1.12 ± 0.54 0.53 ± 0.21 0.30 ± 0.14
a

IC50: 50% concentration required to inhibit SARS-CoV-2 3CLpro. The numbers in the table are the average of three independent tests.