Binding affinity of bisindoles against the human and leishmanial topoisomerase IB enzyme.

Compound no.	Affinity (kcal mol−1)
	Human top I	Leishmanial top IB
2d	−10.1	−10.0
3d	−10.5	−10.5
4a	−11.1	−11.1
12	−8.2	−8.1
13	−11.8	−11.3