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. 1998 Sep;42(9):2391–2398. doi: 10.1128/aac.42.9.2391

TABLE 2.

Renal function in neutropenic patients receiving AmBisome

Dosage cohort (n) Concn in serum (mean ± SD)
Creatinine (mg/dl)
Potassium (meq/liter)
Magnesium (mmol/liter)
Baseline End of therapy Baseline End of therapy Baseline End of therapy
1.0 mg/kg (8) 0.98 ± 0.08 0.83 ± 0.07 3.8 ± 0.19 4.3 ± 0.13 0.81 ± 0.05 0.83 ± 0.03
2.5 mg/kg (8) 0.93 ± 0.08 0.88 ± 0.07 4.2 ± 0.23 3.8 ± 0.15 0.84 ± 0.04 0.86 ± 0.06
5.0 mg/kg (12) 0.95 ± 0.07 1.00 ± 0.13 3.9 ± 0.12 3.6 ± 0.18 0.75 ± 0.03 0.76 ± 0.03
7.5 mg/kg (8) 1.01 ± 0.18 1.41 ± 0.23 4.2 ± 0.22 4.2 ± 0.32 0.68 ± 0.03 0.68 ± 0.04
 All patients (36) 0.95 ± 0.04 1.03 ± 0.08 4.0 ± 0.09 3.9 ± 0.11 0.77 ± 0.02 0.78 ± 0.02