Table 3.
Subgroup analysis of outcomes limited to major hepatectomy.
| All patients (311) | No cell saver (68) | Cell saver (243) | P | |
|---|---|---|---|---|
| Estimated blood loss (ml)a | 1270±69 | 1054±172 | 1327±75 | 0.1 |
| % of blood loss returneda | n/a | 0±0 | 33±1.0 | n/a |
| Tolerance breached, n (%) | 58 (18.6) | 10 (14.7) | 48 (19.5) | 0.4 |
| Breach corrected for blood returned, n (%) | 0 (0) | 28 (58.3) | n/a | |
| Patients requiring allogenic transfusion | ||||
| PRC | 87 (27.8) | 29 (42.6) | 58 (23.9) | 0.004 |
| FFP | 19 (6.1) | 4 (5.9) | 15 (6.2) | 1.0 |
| Plt | 8 (2.6) | 3 (4.4) | 5 (2.1) | 0.4 |
| Total allogenic units transfused | ||||
| PRC | 332 | 129 | 203 | |
| FFP | 120 | 43 | 77 | |
| Plt | 17 | 7 | 10 | n/a |
| Allogenic PRC units per patienta | 1.1±0.18 | 1.9±0.61 | 0.8±0.16 | 0.01 |
| Allogenic FFP units per patienta | 0.4±0.1 | 0.6±0.4 | 0.3±0.1 | 0.2 |
| Allogenic Plt units per patienta | 0.05±0.02 | 0.1±0.06 | 0.04±0.02 | 0.2 |
| Hospital stay (days)b | 6 (5–11) | 6 (5–9) | 7 (5–13) | 0.6 |
| Major complication, n (%) | 42 (13.5) | 10 (14.7) | 32 (13.2) | 0.7 |
| Intervention for postoperative bleeding, n (%) | 4 (1) | 2 (3) | 2 (1) | 0.2 |
| 30-day mortality, n (%) | 7 (2) | 4 (6) | 3 (1) | 0.04 |
| 90-day mortality, n (%) | 13 (4) | 5 (7) | 8 (3) | 0.2 |
Statistically significant P <0.05 values are in bold.
a
Mean±SEM.
b
median (IQR).
FFP, fresh-frozen plasma; Plt, platelets; PRC, packed red cells.