Table 1.
Participant demographics and clinical characteristicsa
| All participants (n = 8) | |
|---|---|
| Age, years | 15 (14, 16) |
| Female, n (%) | 5 (63) |
| Race, n (%) | |
| Whiteb | 7 (88) |
| Asian | 1 (13) |
| Height at screening, cm | 165 (155, 175) |
| Z-scorec | 0.2 (−2.1, 0.8) |
| Weight on day 1, kg | 62 (52, 115) |
| Z-scorec | 0.7 (−0.4, 2.8) |
| Body mass index, kg/m2 | 25 (19, 38) |
| Z-scorec | 1.2 (−0.2, 2.6) |
| Number of adrenal crises within past 2 years | 0 (0, 1) |
| Age at menarche—females, yearsd | 14 (13, 14) |
| Menstrual cycle interval—females, daysd | 28 (21, 56) |
| Glucocorticoid treatment at screening, n (%) | |
| Hydrocortisone alone | 6 (75) |
| Prednisone alone | 2 (25) |
| Glucocorticoid dose (hydrocortisone equivalente), mg/m2/day | 16.2 (11.9, 18.5) |
Values are presented as median (minimum, maximum) unless indicated otherwise.
Includes 1 participant who also self-identified as Hispanic or Latino.
Centers for Disease Control Growth Chart used as reference, with Z-scores based on chronological age.
Based on available data for postmenarchal females (n = 4).
Hydrocortisone equivalents were calculated as 1 mg prednisone = 4 mg hydrocortisone.