Table 4:
G-formula estimation the effect of vancomycin vs. other treatment updated at each time point on 30-days mortality, in the presence of time-varying and time-fixed confounding, stratified by empiric treatment (Time 1).
Population | Intervention | G-formula mean | Mean ratio | Mean difference |
---|---|---|---|---|
All patients (N=427) | 0 – Observed Treatment | 0.07645 | 1.00 (ref) | 0.0000 |
1 – Never treat with vancomycin or switch immediately after empiric treatment | 0.14615 | 1.91 | 0.0696 | |
2 – Always Treat with vancomycin and do not switch to another antibiotict | 0.05005 | 0.65 | −0.0264 | |
Patients received vancomycin at T1 (N=414) | 0 – Observed Treatment | 0.07533 | 1.00 (ref) | 0.0000 |
1 – Never treat with vancomycin or switch immediately after empiric treatment | 0.16744 | 2.22 | 0.0921 | |
2 – Always Treat with vancomycin and do not switch to another antibiotict | 0.04977 | 0.66 | −0.0255 |