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Molecular ions and principal fragments of the biliary metabolites of 5′-ClPAQ in the rata
| Metaboliteb | Retention time (min) | m/z (relative intensity) |
|---|---|---|
| 5′-ClPAAQI | 24 | 466/464 (M+1, 80/100), 393 (52) |
| GS-5′-ClPAQ | 12 | 773/771 (M+1, 90/100), 698 (100), 425 (100), 386 (95) |
| GS-5′-ClPAQ | 14 | 773/771 (M+1, 73/100), 698 (68) |
Four rats were used.
5′-ClPAAQI, 5′-chlorophenylamodiaquine quinoneimine; GS-5′-ClPAQ, 5′-chlorophenylamodiaquine quinoneimine-glutathione adduct.
