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. 2023 Oct 4;13:1255632. doi: 10.3389/fonc.2023.1255632

Table 1.

Characteristics of reports of therapeutic PDT.

Author Year Region Photosensitizer Administration No. of cases Included patients post-BCG (%) Tis (%) Light energy (J/cm2)
Benson (16) 1986 USA Photofrin Intravenous 10 Multifocal Tis 0 10/10 24-45
D’Hallewin (18) 1995 Belgium Photofrin Intravenous 15 Multifocal Tis 3/15 15/15 75-100
D’Hallewin (19) 1997 Belgium 5-ALA Intravesical 6 Recurrent Tis 6/6 6/6 75
Kriegmair (22) 1995 Germany Photofrin Intravenous 21 Recurrent, multifocal NMIBC NA 5/21 15-30
Kriegmair (21) 1996 Germany 5-ALA Intravesical 10 Recurrent NMIBC 10/10 4/10 15-60
Manyak (26) 2003 USA Photofrin Intravenous 34 Recurrent NMIBC 30/34 29/34 20-25
Naito (27) 1991 Japan Photofrin Intravenous 35 Recurrent NMIBC NA 29/35 10-30
Nseyo (28) 2003 USA Photofrin Intravenous 5 Recurrent NMIBC NA 2/5 10-60
Nseyo (29) 1998 USA Photofrin Intravenous 39 Recurrent NMIBC Most 20/39 10-60
Nseyo (30) 1998 USA Photofrin Intravenous 36 Recurrent Tis 36/36 36/36 15
Shumaker (31) 1986 UK Photofrin Intravenous 14 Recurrent Tis NA 14/14 15-25
Uchibayashi (36) 1995 Japan Photofrin Intravenous 34 Recurrent Tis NA 34/34 NA
Unsöld (37) 1990 Germany Photofrin Intravenous 20 Recurrent Tis NA 20/20 15-70
Waidelich (38) 2003 Germany 5-ALA Intravesical 11 Recurrent, multifocal NMIBC NA 9/11 100
Walther (40) 1997 USA Photofrin Intravenous 20 Recurrent NMIBC 5/20 6/20 16.5-25.6
Windahl (41) 1993 Sweden Photofrin Intravenous 10 Refractory NMIBC 1/10 8/10 15-53
Szygula (35) 2001 Poland 5-ALA intravesical 12 NMIBC NA 5/12 10

Tis, Tumor in situ; 5-ALA, 5-aminolevulinic acid; NMIBC, Non-muscle-invasive bladder cancer.