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. 2023 Sep 18;15(9):e45487. doi: 10.7759/cureus.45487

Table 2. Critical appraisal of included studies.

AMSTAR: A MeaSurement Tool to Assess systematic Reviews.

Title Author Type of study Quality assessment tool used Quality score
The longer-term benefits and harms of glucagon-like peptide-1 receptor agonists: a systematic review and meta-analysis Alexander et al. [17] Systematic review and meta-analysis AMSTAR 91%
Heterogeneity of antidiabetic treatment effect on the risk of major adverse cardiovascular events in type 2 diabetes: a systematic review and meta‑analysis D’Andrea et al. [18] Systematic review and meta-analysis AMSTAR 100%
GLP‑1 receptor agonists and cardiorenal outcomes in type 2 diabetes: an updated meta‑analysis of eight CVOTs Giugliano et al. [19] Meta-analysis AMSTAR 91%
The effect of DPP‑4 inhibitors, GLP‑1 receptor agonists and SGLT‑2 inhibitors on cardiorenal outcomes: a network meta‑analysis of 23 CVOTs Giugliano et al. [20] Meta-analysis AMSTAR 91%
Dipeptidyl peptidase-4 inhibitors, glucagon-like peptide 1 receptor agonists and sodium-glucose co-transporter-2 inhibitors for people with cardiovascular disease: a network meta-analysis Kanie et al. [21] Meta-analysis AMSTAR 100%
Effects of GLP-1 receptor agonists on cardiovascular outcomes in patients with type 2 diabetes and chronic kidney disease: a systematic review and meta-analysis Kelly et al. [22] Systematic review and meta-analysis AMSTAR 82%
A meta-analysis evaluating indirectly GLP-1 receptor agonists and arrhythmias in patients with type 2 diabetes and myocardial infarction Liu et al. [23] Meta-analysis AMSTAR 82%
Glucagon‑like peptide‑1 (GLP‑1) receptor agonists and cardiovascular events in patients with type 2 diabetes mellitus: a meta‑analysis of double‑blind, randomized, placebo‑controlled clinical trials Qin et al. [24] Meta-analysis AMSTAR 100%
Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis Sattar et al. [25] Meta-analysis AMSTAR 82%
Effects of GLP-1 receptor agonists on arrhythmias and its subtypes in patients with type 2 diabetes: a systematic review and meta-analysis Wei et al. [26] Systematic review and meta-analysis AMSTAR 91%
Risk of stroke and retinopathy during GLP-1 receptor agonist cardiovascular outcome trials: an eight RCTs meta-analysis Wei et al. [27] Meta-analysis AMSTAR 82%
Cardiovascular and renal outcomes with SGLT‑2 inhibitors versus GLP‑1 receptor agonists in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and network meta‑analysis Yamada et al. [28] Systematic review and meta-analysis AMSTAR 91%
The potential of glucagon-like peptide-1 receptor agonists in heart failure Kreiner et al. [29] Narrative review SANRA 92%
GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes Marx et al. [30] Narrative review SANRA 92%