Table 3.

z-scores of the aortic annulus, Sinus Valsalva Aortae, and sinotubular junction before and after initiation of angiotensin receptor blocker (ARB) and beta blocker (BB) therapy

	ARB	BB	p-value
Before treatment
Z-Score annulus	1.41 ± 1.19	1.51 ± 1.36	0.814
Z-Score Sinus Valsalva	1.88 ± 1.03	2.66 ± 1.59	0.101
Z-Score sinotubular junction	0.96 ± 0.97	1.74 ± 1.06	< 0.05 (0.022)
At follow-up
Z-Score annulus	1.20 ± 1.11	2.10 ± 1.28	< 0.05 (0.016)
Z-Score Sinus Valsalva	1.68 ± 1.01	2.86 ± 1.50	< 0.05 (0.013)
Z-Score sinotubular junction	0.76 ± 0.92	2.16 ± 1.31	< 0.01 (0.000)
Difference*
Z-Score annulus	-0.21 ± 0.95	0.59 ± 0.88	< 0.05 (0.010)
Z-Score Sinus Valsalva	-0.20 ± 0.41	0.20 ± 0.33	< 0.01 (0.001)
Z-Score sinotubular junction	-0.20 ± 0.75	0.42 ± 1.01	< 0.05 (0.021)

ARB angiotensin-receptor-blocker (n = 75), BB betablocker (n = 14)

Age in years (average): ARB = 8,1 / BB = 10 / p = 0.179

*between z-score values before therapy initiation and follow-up after therapy initiation