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. 2023 Oct 11;46(10):1021–1037. doi: 10.1007/s40264-023-01342-z

Table 2.

Description of unintentional medication discrepancies  (UMDs)

Stage of service implementation Total frequency
Pre-stage Post-stage
Patient affected by UMDs 23 (13.6%) 29 (11.9%) 52 (12.7%)
Gender
 Male 11 (6.5%) 11 (4.5%) 22 (5.3%)
 Female 12 (7.1%) 18 (7.4%) 30 (7.2%)
Age, years
 > 65 5 (2.9%) 7 (2.8%) 12 (2.9%)
 ≤ 65 18 (10.7%) 21(8.6%) 39 (9.4%)
Total number of included patients in the stage 168 (100%) 243 (100%) 411 (100%)
Nature of the UMD
Medication affected by UMDs 41 48 89
Medication discrepancy severity (NCC MERP criteria)
A: Circumstances or events that have the capacity to cause error 26 (63.4%) 30 (62.5%) 56 (63%)
B: An error occurred but the error did not reach the patient 6 (14.6%) 7 (14.5%) 13 (14.6%)
C: An error occurred that reached the patient but did not cause patient harm 2 (4.8%) 9 (18.7%) 11 (12.3%)
D: An error occurred that reached the patient and required monitoring to confirm that it resulted in no harm to the patient and/or required intervention to preclude harm 6 (14.6%) 1 (2%) 7 (7.8%)
E: An error occurred that may have contributed to or resulted in temporary harm to the patient and required intervention 1 (2.4%) 0 1 (1.1%)
Missing data 0 1 (2%) 1 (1.1%)
Medication discrepancy harma
Potential harm 37 (90.2%) 45 (94%) 82 (92.1%)
No harm 3 (7.3%) 1 (2%) 4 (4.4%)
Actual harm 1 (2.4%) 0 1 (1.1%)
Missing data 0 2 (4%) 2 (2.2%)
Total medications affected by UMDs 41 (100%) 48 (100%) 89 (100%)
Medication class based on British National Formulary chapters
Cardiovascular system 20 19 39 (43.8%)
           Angiotensin-converting enzyme (ACE) inhibitors 4 6
           Diuretics 5 3
Central nervous system 6 9 15 (16.8%)
          Opioids 4 1
Gastrointestinal system 4 5 9 (10.1%)
         Laxatives 3 4
Endocrine system 2 3 5 (5.6%)
Respiratory system 2 3 5 (5.6%)
Blood and blood-forming organs 1 3 4 (4.4%)
Musculoskeletal system 1 2 3 (3.3%)
Skin 1 2 3 (3.3%)
Genito-urinary system 1 1 2 (2.2%)
Nutrition and metabolic disorders 1 1 2 (2.2%)
Anti-infective system 1 0 1 (1.1%)
Eye 0 1 1 (1.1%)

NCC MERP National Coordinating Council for Medication Error Reporting and Prevention, UMDs unintentional medication discrepancies

aCategorised based on the NCC MERP