Table 2.
Baseline medication and laboratory parameters
| Anticoagulation before randomization | |||
| FALSE | 23 (41.8%) | 22 (39.3%) | 45 (40.5%) |
| TRUE | 32 (58.2%) | 34 (60.7%) | 66 (59.5%) |
| ASS | |||
| Yes | 18 (32.7%) | 24 (42.9%) | 42 (37.8%) |
| ACE inhibitors | |||
| Yes | 15 (27.3%) | 15 (26.8%) | 30 (27.0%) |
| Aldosterone antagonists | |||
| Yes | 3 (5.5%) | 0 (0.0%) | 3 (2.7%) |
| Angiotensin II receptor blockers (ARBs) | |||
| Yes | 10 (18.2%) | 13 (23.2%) | 23 (20.7%) |
| Antibiotics | |||
| Yes | 23 (41.8%) | 23 (41.1%) | 46 (41.4%) |
| Antibodies/Immunomodulators | |||
| Yes | 2 (3.6%) | 2 (3.6%) | 4 (3.6%) |
| Antivirals | |||
| Yes | 4 (7.3%) | 6 (10.7%) | 10 (9.0%) |
| Beta blocking agents | |||
| Yes | 14 (25.5%) | 17 (30.4%) | 31 (27.9%) |
| Clopidogrel | |||
| Yes | 1 (1.8%) | 1 (1.8%) | 2 (1.8%) |
| Diuretics | |||
| Yes | 15 (27.3%) | 13 (23.2%) | 28 (25.2%) |
| Glucocorticoids | |||
| Yes | 37 (67.3%) | 36 (64.3%) | 73 (65.8%) |
| HMG CoA reductase inhibitors | |||
| Yes | 7 (12.7%) | 8 (14.3%) | 15 (13.5%) |
| NSAIDs | |||
| Yes | 4 (7.3%) | 3 (5.4%) | 7 (6.3%) |
| Proton pump inhibitors | |||
| Yes | 28 (50.9%) | 29 (51.8%) | 57 (51.4%) |
| d-Dimer (mg/L) | |||
| N-Miss | 1 | 1 | 2 |
| Mean (SD) | 2.119 (3.024) | 2.451 (4.622) | 2.287 (3.898) |
| Range | 0.800–21.792 | 0.845–35.020 | 0.800–35.020 |
| d-Dimer > 2 ULN | |||
| No | 11 (20.4%) | 10 (18.2%) | 21 (19.3%) |
| Yes | 43 (79.6%) | 45 (81.8%) | 88 (80.7%) |
| Creatinine clearance (mL/min) | |||
| Mean (SD) | 106.561 (42.550) | 110.597 (51.584) | 108.541 (47.021) |
| > 0.5 ULN (+ age dep. adapt) | |||
| N-Miss | 1 | 1 | 2 |
| FALSE | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| TRUE | 54 (100.0%) | 55 (100.0%) | 109 (100.0%) |