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. 2022 Aug 26;112(11):1529–1540. doi: 10.1007/s00392-022-02086-z

Table 2.

Clinical characteristics of participants with persistent normal aortic root (AR) diameter and with new AR dilatation categorized in three groups according to absolute AR diameter, AR indexed to body surface area (BSA) and AR indexed to height

No new AR dilatation New AR dilatation p value No new AR/BSA dilatation New AR/BSA dilatation p value No new AR/height dilatation New AR/height dilatation p value
N 386 66 423 34 419 42
Age, years 40.35 ± 9.57 44.45 ± 9.16 0.0013 40.77 ± 9.63 45.8 ± 8.64 0.0033 40.46 ± 9.54 46.92 ± 7.99  < .0001
BMI, Kg/m2 24.07 ± 3.5 25 ± 3.01 0.0424 24.36 ± 3.5 23.79 ± 3 0.3601 24.12 ± 3.42 25.34 ± 3.58 0.0299
Male, % 178 (46.11%) 40 (60.61%) 0.0295 201 (47.52%) 22 (64.71%) 0.0537 201 (47.97%) 23 (54.76%) 0.4012
Office SBP, mmHg 121.33 ± 14.7 124.33 ± 16.57 0.1333 121.45 ± 14.86 126.35 ± 15.95 0.0661 121.38 ± 14.63 126.19 ± 17.15 0.0462
Office DBP, mmHg 79.89 ± 9.63 83.03 ± 9.95 0.0151 80.16 ± 9.6 83.47 ± 10.58 0.0555 80.01 ± 9.57 84.1 ± 10.33 0.0092
Office PP, mmHg 41.45 ± 9.2 41.3 ± 10.75 0.9097 41.3 ± 9.43 42.1 ± 8.33 0.3427 41.37 ± 9.34 42.1 ± 10 0.6314
Office HR, b/min 70.86 ± 9.34 68.36 ± 9.57 0.0458 70.42 ± 9.48 69.76 ± 10.44 0.7008 70.56 ± 9.46 68.48 ± 9.63 0.1755
24 h SBP, mmHg 115.79 ± 8.91 117.39 ± 9.86 0.1842 116.05 ± 9.03 115.31 ± 9.06 0.6468 115.88 ± 8.97 117.65 ± 9.71 0.2269
24 h DBP, mmHg 72.62 ± 6.45 75.31 ± 7.12 0.0022 72.94 ± 6.59 74.4 ± 6.5 0.2150 72.76 ± 6.52 76.17 ± 6.7 0.0014
24 h PP, mmHg 43.16 ± 4.87 42.08 ± 4.95 0.0976 43.07 ± 4.88 40.66 ± 4.51 0.0115 43.13 ± 4.88 41.49 ± 4.71 0.0381
24 h HR, b/min 76.42 ± 8.22 75.66 ± 8.64 0.4928 76.33 ± 8.48 74.76 ± 7.94 0.2971 76.24 ± 8.36 76.23 ± 8.91 0.9925
Antihypertensive drugs, % 22 (5.74%) 2 (3.03%) 0.5547 28 (6.62%) 1 (2.94%) 0.7129 25 (6.01%) 2 (4.76%) 1.0000
ARD, cm 2.97 ± 0.3 3.32 ± 0.25  < 0.0001 3.02 ± 0.33 3.28 ± 0.33  < 0.0001 3.01 ± 0.32 3.32 ± 0.31  < 0.0001
ARD follow-up, cm 3.16 ± 0.31 3.83 ± 0.28  < 0.0001 3.23 ± 0.37 3.81 ± 0.4  < 0.0001 3.21 ± 0.35 3.88 ± 0.34  < 0.0001
ARD, cm/m2 1.74 ± 0.16 1.82 ± 0.17 0.0001 1.74 ± 0.16 1.89 ± 0.15  < 0.0001 1.74 ± 0.16 1.87 ± 0.17  < 0.0001
ARD follow-up, cm/m2 1.8 ± 0.18 2.06 ± 0.18  < 0.0001 1.81 ± 0.18 2.24 ± 0.11  < 0.0001 1.8 ± 0.18 2.17 ± 0.16  < 0.0001
ARD, cm/m 1.8 ± 0.16 1.96 ± 0.14  < 0.0001 1.82 ± 0.17 1.97 ± 0.16  < 0.0001 1.82 ± 0.16 1.99 ± 0.16  < 0.0001
ARD follow-up, cm/m 1.92 ± 0.16 2.27 ± 0.11  < 0.0001 1.95 ± 0.19 2.31 ± 0.15  < 0.0001 1.94 ± 0.17 2.36 ± 0.1  < 0.0001
Total cholesterol, mg/dL 211.62 ± 38.39 220.15 ± 51.33 0.1165 212.65 ± 40.63 215.97 ± 41.2 0.6469 211.66 ± 39.23 222.4 ± 52.28 0.1025
HDL cholesterol, mg/dL 56.99 ± 14.61 57.05 ± 19.78 0.9810 56.47 ± 14.53 59.81 ± 23.07 0.2221 56.94 ± 14.79 55.95 ± 20.75 0.6894
Glycemia, mg/dL 85.67 ± 11.38 88.75 ± 15.71 0.0887 85.85 ± 11.25 91.53 ± 19.83 0.0347 85.64 ± 11.07 91.31 ± 18.73 0.0154
Triglycerides, mg/dL 95.15 ± 54.09 101.48 ± 54.15 0.1462 96.37 ± 54.44 96.47 ± 47.26 0.6421 94.63 ± 52.61 107.71 ± 62.86 0.1078
LVH, % 19 (5.38%) 3 (4.84%) 1.0000 21 (5.34%) 2 (6.25%) 0.6883 21 (5.44%) 2 (5.26%) 1.0000
LVMI, g/m2 78.85 ± 16.75 84.19 ± 16.21 0.0204 79.69 ± 16.81 85.29 ± 18.12 0.0722 79.6 ± 16.82 83.48 ± 18.01 0.1781

For abbreviations see Table 1