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High-flow nasal cannula (HFNC) oxygen therapy applied after extubation decreases work of breathing and respiratory rate. HFNC reduces inspiratory esophageal pressure swings (A) and pressure–time product per minute (B) in comparison with standard oxygen This indicates a lower metabolic cost and respiratory effort associated with the use of HFNC. Horizontal red lines represent median values. P values were calculated using a two-way repeated measures ANOVA
