Table 3.
Effects on high-flow nasal cannula versus standard oxygen on hemodynamics and cardiac biomarkers
| Variable | Standard oxygen | HFNC | p value |
|---|---|---|---|
| Systolic arterial pressure, mmHg | 143 ± 19 | 140 ± 19 | 0.238 |
| Diastolic arterial pressure, mmHg | 73 ± 15 | 71 ± 14 | 0.427 |
| Mean arterial pressure, mmHg | 98 ± 14 | 96 ± 13 | 0.310 |
| Heart rate, bpm | 85 ± 12 | 86 ± 12 | 0.238 |
| CVP, mmHg | 3 [1–7] | 4 [1–6] | 0.792 |
| SvcO2, % | 75 ± 10 | 75 ± 7 | 0.750 |
| Pv-aCO2 gap | 2.5 ± 1.9 | 3.4 ± 2.2 | 0.273 |
| NT-proBNP, pg/ml | 355 [152–901] | 329 [147–962] | 0.314 |
| Troponin T, pg/ml | 17.2 [10.5–29.9] | 19.1 [10.3–32.0] | 0.206 |
Abbreviations: HFNC: high-flow nasal cannula; SvcO2: central venous oxygen saturation; CVP: central venous pressure; Pv-aCO2 gap: venous-to-arterial carbon dioxide gap; NT-proBNP: N-terminal pro-B-type natriuretic peptide. Normally distributed variables are expressed as mean ± standard deviation; non-normal distributed variables are expressed as median and [interquartile range]. p values were calculated using a two-way repeated measures ANOVA