TABLE 2.
State of C. albicans infection in monolayers of murine peritoneal macrophages in the absence of antifungal agents
Time after C. albicans phago- cytosis (h) | % (mean ± SD) of total macrophagesa:
|
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---|---|---|---|---|---|
Uninfected | Infected
|
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Total | With blasto- spores | With blasto- spores, germ tubes, and hyphae | With germ tubes and hyphae | ||
0 | 32.9 ± 4.0 | 67.1 ± 4.0 | 66.9 ± 4.0 | 0.2 ± 0.2 | 0.0 ± 0.0 |
4 | 22.7 ± 2.1 | 77.3 ± 2.2 | 6.4 ± 4.4 | 6.0 ± 3.2 | 64.9 ± 8.5 |
24 | 0.0 ± 0.0 | 100.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 100.0 ± 0.0 |
Each value represents the mean of 15 separate experiments; in each experiment a total of 150 macrophages were scanned.