Table 3.
Docking scores and ΔG of protein–protein complexes obtained from the Cluspro and PRODIGY servers.
| Protein–Protein Complex | Docking score | ΔG (kcal mol−1) | Dissociation constant (M) |
|---|---|---|---|
| DARPin::HAS | −732.3 | −9.6 | 1.7e−07 |
| nGLP1-DARPin::HAS | −752.3 | −9.2 | 1.8e−07 |
| mGLP1-DARPin-1::HAS | −746.2 | −8.1 | 3.9e−06 |
| mGLP1-DARPin-2::HAS | −810.6 | −8.6 | 1.7e−07 |
| GLP-1::GLP-1 receptor | −820.6 | −6.8 | 1.6e−05 |
| nGLP1-DARPin::GLP-1 receptor | −897.4 | −6.1 | 3.2e−06 |
| mGLP1-DARPin-1::GLP-1 receptor | −821.9 | −5.5 | 3.4e−05 |
| mGLP1-DARPin-2::GLP-1 receptor | −852.3 | −5.8 | 1.2e−05 |