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. 2023 Oct 18;9(1):74. doi: 10.1038/s41537-023-00404-6

Table 1.

SNPs included in regression analyses exploring the impact of pharmacogenomic variation neutrophil levels.

SNP CHR Gene ALT Main Association
rs2011425 2 UGT1A4/5/6/7/8/9/10 G Alternative allele linked with decreased plasma norclozapine levels29.
rs61750900 4 UGT2B10 T Alternative allele linked with decreased plasma norclozapine levels29.
rs1126545 10 CYP2C18 T Alternative allele linked with increased metabolic ratio29.
rs2472297 15 CYP1A1/2 T Alternative allele linked with decreased plasma clozapine levels29.
rs2814778 1 ACKR1 C Alternative allele homozygosity (Duffy-Null genotype) linked with non-pathological baseline ANC31.

SNPs included in regression analyses exploring the impact of pharmacogenomic variation on neutrophil levels.

SNP Single Nucleotide Polymorphism, CHR Chromosome, ALT Alternative (or Minor) allele.