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. 2023 Oct 5;14:1242050. doi: 10.3389/fendo.2023.1242050

Table 2.

Metabolic profile in PCOS with thyroid disease.

Participants Metabolic profile Ref
Study group Control group
114 PCOS patients with SCH 253 PCOS patients without SCH Exacerbated the metabolic disorders (insulin resistance and dyslipidemia) in PCOS patients with SCH (35)
20 patients with PCOS and SCH 39 patients with PCOS and normal thyroid function and 53 healthy women with normal thyroid function Dyslipidemia with higher triglyceride levels and insulin resistance in group with PCOS and subclinical hypothyroidism (37)
148 women with PCOS, without Type 2 diabetes mellitus (T2DM) and CVD present at baseline At baseline, prevalent prediabetes was present in 18 (12%) of PCOS cases and it progressed to T2DM in 5 (3%) of the cases. Incident prediabetes during the follow-up was noted in 47 (32%) women or 4.7 per 1000 persons/year. cardiovascular risk in PCOS women with prediabetes was high. (38)
100 females with PCOS 100 normal controls Significantly higher HOMA-IR and frequency of subjects with dyslipidemia in SCH PCOS subjects (39)
583 women with PCOS Patients with elevated TSH levels had significantly increased fasting insulin and total cholesterol (TC)/high-density lipoprotein cholesterol (HDL) ratio. (40)