Table 2.
Metabolic profile in PCOS with thyroid disease.
Participants | Metabolic profile | Ref | |
---|---|---|---|
Study group | Control group | ||
114 PCOS patients with SCH | 253 PCOS patients without SCH | Exacerbated the metabolic disorders (insulin resistance and dyslipidemia) in PCOS patients with SCH | (35) |
20 patients with PCOS and SCH | 39 patients with PCOS and normal thyroid function and 53 healthy women with normal thyroid function | Dyslipidemia with higher triglyceride levels and insulin resistance in group with PCOS and subclinical hypothyroidism | (37) |
148 women with PCOS, without Type 2 diabetes mellitus (T2DM) and CVD present at baseline | At baseline, prevalent prediabetes was present in 18 (12%) of PCOS cases and it progressed to T2DM in 5 (3%) of the cases. Incident prediabetes during the follow-up was noted in 47 (32%) women or 4.7 per 1000 persons/year. cardiovascular risk in PCOS women with prediabetes was high. | (38) | |
100 females with PCOS | 100 normal controls | Significantly higher HOMA-IR and frequency of subjects with dyslipidemia in SCH PCOS subjects | (39) |
583 women with PCOS | Patients with elevated TSH levels had significantly increased fasting insulin and total cholesterol (TC)/high-density lipoprotein cholesterol (HDL) ratio. | (40) |