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. 2023 Oct 5;14:1242536. doi: 10.3389/fimmu.2023.1242536

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Copyright © 2023 Peterhoff, Wiegrebe, Einhauser, Patt, Beileke, Günther, Steininger, Niller, Burkhardt, Küchenhoff, Gefeller, Überla, Heid and Wagner

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flow chart to illustrate the selection of the samples. At baseline, 4185 serum samples were collected. Of these samples, 352 were positive in a latent class analysis (LCA) of three SARS-CoV-2 antibody tests. Of these participants, 319 attended the next two visits, follow up 1 (FU1) and follow up 2 (FU2), with 211 participants not vaccinated at the time of FU2. These 211 participants (blue highlighted box) represent the study collective.