Table 2.
Assays used in this study.
Abbreviation | Manufacturer | Antigen (domain) | Isotype | characteristic |
---|---|---|---|---|
Binding | ||||
S Elecsys Ig | Roche | S (receptor-binding domain) | total Ig | quantitative Ig |
N Elecsys Ig | Roche | N (unknown) | total Ig | quantitative Ig |
S RBD IgG | in-house | S (receptor-binding domain) | IgG | quantitative IgG |
S RBD IgA | in-house | S (receptor-binding domain) | IgA | quantitative IgA |
S RBD IgM | in-house | S (receptor-binding domain) | IgM | quantitative IgM |
S ecto IgG | in-house | S (ectodomain) | IgG | quantitative IgG |
N NTD IgG | in-house | N (N-terminal domain) | IgG | quantitative IgG |
N CTD IgG | in-house | N (C-terminal domain) | IgG | quantitative IgG |
Neutralization | ||||
Neutralization | in-house | S (complete) | total Ig | qualitative and quantitative Ig |
Avidity | ||||
S RBD IgG AI | in-house | S (receptor-binding domain) | IgG | qualitative, avidity |
S ecto IgG AI | in-house | S (ectodomain) | IgG | qualitative, avidity |
N NTD IgG AI | in-house | N (N-terminal domain) | IgG | qualitative, avidity |
N CTD IgG AI | in-house | N (C-terminal domain) | IgG | qualitative, avidity |
(S, spike protein; N, nucleocapsid protein; Ig, immunglobuline).