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. 2023 Oct 5;14:1221442. doi: 10.3389/fendo.2023.1221442

Table 1.

MR results of air pollution effects on obesity traits by IVW.

Exposure Outcome nSNP Beta LCI UCI p
PM2.5 ASAT 240 0.12 0.023 0.21 1.49E-02
BMI 99 0.082 0.024 0.14 5.73E-03
HC 119 0.058 -0.043 0.16 2.63E-01
OB1 113 0.38 0.11 0.65 6.31E-03
OB2 113 0.37 -0.048 0.79 8.27E-02
OB3 113 0.54 -0.21 1.30 1.59E-01
VAT 240 0.093 0.0026 0.18 4.38E-02
WC 118 0.094 0.0099 0.18 2.85E-02
WHR 119 0.074 -0.010 0.16 8.44E-02
NO2 ASAT 283 0.013 -0.083 0.11 7.87E-01
BMI 110 0.013 -0.047 0.074 6.69E-01
HC 133 0.10 0.0057 0.19 3.77E-02
OB1 127 0.33 0.055 0.61 1.90E-02
OB2 127 0.35 -0.10 0.80 1.27E-01
OB3 123 0.59 -0.13 1.31 1.10E-01
VAT 283 -0.0042 -0.090 0.081 9.23E-01
WC 131 0.090 0.0092 0.17 2.90E-02
WHR 132 0.077 -0.0093 0.16 8.04E-02
NOx ASAT 240 0.070 -0.034 0.17 1.87E-01
BMI 99 0.062 0.00044 0.12 4.84E-02
HC 119 0.16 0.060 0.26 1.74E-03
OB1 113 0.28 0.019 0.55 3.60E-02
OB2 113 0.66 0.24 1.07 1.85E-03
OB3 113 1.16 0.42 1.90 2.10E-03
VAT 240 0.048 -0.047 0.14 3.20E-01
WC 118 0.15 0.057 0.24 1.61E-03
WHR 119 0.13 0.036 0.22 6.37E-03

Beta = log (OR). P < 0.05 were bolded.

PM2.5, Particulate matter air pollution; NO2, Nitrogen dioxide; NOX, Nitrogen oxides; ASAT, abdominal subcutaneous adipose tissue; BMI, body mass index; HC, hip circumference; OB1, obesity class 1; OB2, obesity class 2; OB3, obesity class 3; VAT, visceral adipose tissue; WC, waist circumference; WHR, waist-to-hip ratio; UCI, Upper confidence interval; LCI, Lower confidence interval.