Comparison 7. Specific anticonvulsants (topiramate) versus specific other medications (naltrexone).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Dropouts	3	385	Risk Ratio (M‐H, Random, 95% CI)	0.79 [0.52, 1.19]
2 Severe relapse, dichotomous outcome	2	284	Risk Ratio (M‐H, Random, 95% CI)	0.54 [0.36, 0.81]
3 Continuous abstinence, dichotomous outcome	3	385	Risk Ratio (M‐H, Random, 95% CI)	1.18 [0.94, 1.49]
4 Craving (OCDS total score)	2	257	Mean Difference (IV, Random, 95% CI)	‐2.74 [‐4.28, ‐1.21]