Clinical outcome in patients with atopic dermatitis (AD) treated with dupilumab. A, Eczema Area and Severity Index (EASI) score, (C) Investigator Global Assessment (IGA) score, (B) percentage of improvement in EASI, and (D) IGA during different visits of patients with AD and dupilumab–associated ocular surface disease (DAOSD). Data are presented in box and whisker plots showing minimum, maximum, and median values; a diminutive (+) indicates mean values, () gray dotted lines indicate the mean value at baseline in AD, and () orange dotted lines indicate the mean value at baseline in DAOSD. N = 6–14. One-way analysis of variance was used for statistical testing. NA = not applicable.