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. 2023 Oct 18;8(12):1165–1173. doi: 10.1001/jamacardio.2023.3379

Table 2. Baseline Characteristics of Patients With CIED Infection According to Extraction.

Characteristic Patientsa
No extraction within 30 d (n = 9202) Extraction at <7 d (n = 1511) Extraction at 7-30 d (n = 591) P value
Age at infection, median (IQR), y 75.0 (67.0-82.0) 75.0 (68.0-81.0) 75.0 (66.0-80.0) .06
Age group at infection, y
<65 1941 (21.1) 300 (19.9) 139 (23.5) <.001
65 to <75 2512 (27.3) 447 (29.6) 153 (25.9)
75 to <85 3227 (35.1) 565 (37.4) 229 (38.7)
≥85 1522 (16.5) 199 (13.2) 70 (11.8)
Sex
Female 3852 (41.9) 478 (31.6) 175 (29.6) <.001
Male 5350 (58.1) 1033 (68.4) 416 (70.4)
Race
Black 1554 (16.9) 159 (10.5) 60 (10.2) <.001
White 6941 (75.4) 1278 (84.6) 503 (85.1)
Otherb 707 (7.7) 74 (4.9) 28 (4.7)
Comorbidities
Dementia 1213 (13.2) 111 (7.3) 48 (8.1) <.001
Diabetes 6478 (70.4) 889 (58.8) 357 (60.4) <001
Ischemic heart disease 8411 (91.4) 1345 (89.0) 524 (88.7) .002
Peripheral vascular disease 6215 (67.5) 817 (54.1) 327 (55.3) <.001
Congestive heart failure 8081 (87.8) 1261 (83.5) 484 (81.9) <.001
Cerebrovascular disease 4984 (54.2) 662 (43.8) 267 (45.2) <.001
Hypertension 9072 (98.6) 1471 (97.4) 572 (96.8) <.001
COPD 6616 (71.9) 973 (64.4) 400 (67.7) <.001
Kidney disease 6869 (74.6) 820 (54.3) 311 (52.6) <.001
Stroke or TIA 3468 (37.7) 415 (27.5) 170 (28.8) <.001
Myocardial infarction 4310 (46.8) 700 (46.3) 292 (49.4) .43
Cancer 2318 (25.2) 347 (23.0) 157 (26.6) .12
Valvular heart disease 7565 (82.2) 1147 (75.9) 441 (74.6) <.001
Device type
CRTD or CRTP 1354 (14.7) 277 (18.3) 100 (16.9) <.001
Pacemaker 5247 (57.0) 723 (47.8) 271 (45.9)
ICD 2601 (28.3) 511 (33.8) 220 (37.2)
Geographic region
Midwest 2155 (23.4) 389 (25.7) 151 (25.5) .03
Northeast 1719 (18.7) 242 (16.0) 85 (14.4)
South 3865 (42.0) 650 (43.0) 261 (44.2)
West or other 1463 (15.9) 230 (15.2) 94 (15.9)
Dual Medicaid eligibility 3522 (38.3) 443 (29.3) 182 (30.8) <.001
Time since device implantation, median (IQR), y 2.9 (1.8-4.9) 3.2 (1.8-5.6) 3.5 (2.1-5.8) <.001
Claims-based frailty indicator 3606 (39.2) 411 (27.2) 159 (26.9) <.001
Frailty index score, median (IQR) 0.2 (0.1-0.4) 0.2 (0.1-0.3) 0.2 (0.1-0.3) <.001

Abbreviations: CIED, cardiac implantable electronic device; COPD, chronic obstructive pulmonary disease; CRTD, cardiac resynchronization therapy defibrillator; CRTP, cardiac resynchronization therapy pacemaker; ICD, implantable cardioverter defibrillator; TIA, transient ischemic attack.

a

Data are presented as the number (percentage) of patients unless otherwise indicated.

b

Included Asian, Hispanic, North American Native, unknown, and other (not broken down further due to small cell sizes and complying with the Centers for Medicare & Medicaid Services cell suppression policy).