Table 3. Comparison of FA and MD values between the 2 groups.

ROI	Parameter	NEC group (n=30)	Control group (n=40)	t or Z value	P value	Q value
SCC	FA	0.44±0.07	0.62±0.07	−8.214	<0.001*	0.02**
	MD	1.102±0.076	1.074±0.080	−1.482	0.143	0.26
LN	FA	0.09±0.02	0.14±0.04	−4.932	<0.001*	0.01**
	MD	1.059±0.112	0.999±0.108	2.246	0.028*	0.093**
CN	FA	0.05±0.02	0.06±0.02	−1.908	0.063	0.14
	MD	1.148±0.133	1.114±0.155	−0.984	0.329	0.47
TH	FA	0.16±0.02	0.17±0.04	−0.792	0.443	0.554
	MD	1.062±0.084	1.045±0.084	−0.826	0.412	0.549
FWM	FA	0.06±0.02	0.08±0.03	−2.965	0.005*	0.02**
	MD	1.194±0.115	1.138±0.108	−2.090	0.040*	0.114
PWM	FA	0.10±0.03	0.11±0.04	−0.691	0.493	0.548
	MD	1.187±0.236	1.053±0.538	−1.278	0.209	0.322
OWM	FA	0.11±0.03	0.11±0.03	−0.176	0.861	0.861
	MD	1.299±0.251	1.218±0.216	1.453	0.151	0.252
CERE	FA	0.09±0.02	0.11±0.03	−1.539	0.131	0.262
	MD	0.944±0.273	0.912±0.962	−0.692	0.492	0.579
PLIC	FA	0.37 (0.31–0.48)	0.56 (0.52–0.61)	−5.071	<0.001*	0.01**
	MD	1.182±0.116	1.017±0.179	4.394	<0.001*	0.005**
CP	FA	0.13 (0.10–0.17)	0.16 (0.14–0.18)	−1.987	0.047*	0.1175
	MD	1.083±0.121	1.072±0.277	0.229	0.820	0.863

Data are expressed as the mean ± SD or median (range). The NEC group had significantly lower FA values for the SCC (P<0.001), PLIC (P<0.001), LN (P<0.001), FWM (P=0.005), and CP (P=0.047). *, P value <0.05; **, Q value <0.1. FA, fractional anisotropy; MD, mean diffusivity; ROI, region of interest; NEC, necrotizing enterocolitis; SCC, splenium of the corpus callosum; LN, lentiform nucleus; CN, caudate nucleus; TH, thalamus; FWM, frontal white matter; PWM, parietal white matter; OWM, occipital white matter; CERE, cerebellum; PLIC, posterior limbs of the internal capsule; CP, cerebral peduncle; SD, standard deviation.