TABLE 2.

Antimalarial activities of substituted benzohydroxamic acids^a

Compound	Structure	IC50 (μM)	95% upper bound (μM)	95% lower bound (μM)	No. of tests
VF 149		6.4	25.7	<1	76
VF 147		15.5	35.5	3.0	68
VF 236		23	80	3.5	52
VF 233		38	185	9.2	51
VF 368		301	>2,000	46	51
VF 268		589	>2,000	91	51
VF 282		2,010	>10,000	520	52

^aRNR inhibitors synthesized in one of our laboratories (H.L.E.) were tested on P. falciparum cultures.