Table 3. Comparison of MRI features between mass-forming ICC and atypical HCC.
| Variables | Mass-forming ICC (n=53) | Atypical HCC (n=76) | χ2/t | P value |
|---|---|---|---|---|
| Shape | 1.772 | 0.412 | ||
| Irregular | 32 (60.4) | 37 (48.7) | ||
| Lobulated | 9 (17.0) | 18 (23.7) | ||
| Globular | 12 (22.6) | 21 (27.6) | ||
| Location | ||||
| Right liver lobe | 36 (67.9) | 54 (71.1) | 0.439 | 0.803 |
| Left liver lobe | 11 (20.8) | 16 (21.1) | ||
| Caudate lobe | 6 (11.3) | 6 (7.9) | ||
| Maximum diameter (mm) | 29.1±5.7 | 31.1±5.9 | 1.932 | 0.056 |
| Central hyperintensity on T2WI | 21 (39.6) | 17 (22.4) | 4.473 | 0.034 |
| Central hypointensity on T2WI | 36 (67.9) | 34 (44.7) | 6.765 | 0.009 |
| Multifocal hyperintensity on T2WI | 5 (9.4) | 20 (26.3) | 5.696 | 0.017 |
| Nodule in nodule | 6 (11.3) | 11 (14.5) | 0.271 | 0.602 |
| Mosaic sign | 11 (20.8) | 21 (27.6) | 0.792 | 0.374 |
| Rim APHE | 27 (50.9) | 31 (40.8) | 1.301 | 0.254 |
| Peripheral washout | 6 (11.3) | 8 (10.5) | 0.020 | 0.887 |
| Peripheral enhancement | 41 (77.4) | 62 (81.6) | 0.346 | 0.557 |
| Capsule sign | 3 (5.7) | 22 (28.9) | 10.838 | 0.001 |
| Targetoid sign | 46 (86.8) | 8 (10.5) | ||
| Targetoid sign on HBP | 40 (75.5) | 7 (9.2) | 59.195 | <0.001 |
| Targetoid restriction on DWI | 44 (83.0) | 8 (10.5) | 68.198 | <0.001 |
Data are number of patients (percentage) or mean ± standard deviation. The maximum diameter comparisons were performed using the independent samples t-test. Except where noted, data were compared using the χ2 test. MRI, magnetic resonance imaging; ICC, intrahepatic cholangiocarcinoma; HCC, hepatocellular carcinoma; T2WI, T2-weighted imaging; APHE, arterial phase hyperenhancement; HBP, hepatobiliary phase; DWI, diffusion-weighted imaging.