Table 5.
Potential Relevance of PROMs to BEST Categories
| Diagnostic | Monitoring | Predictive | Prognostic | Pharmacodynamic/Response | Safety | Susceptibility/Risk | |
|---|---|---|---|---|---|---|---|
| NEI VFQ-25 | X | ||||||
| DR-U | X | ||||||
| RetDQoL | |||||||
| IVI | X | ||||||
| RetCAT | X | ||||||
| EQ-5D | |||||||
| EQ-5D/VAS | |||||||
| SF-6D | |||||||
| HUI3 | |||||||
| VisQoL | |||||||
| TTO | |||||||
| SG |
BEST = Biomarkers, EndpointS, and other Tools; DR-U = Diabetic Retinopathy Utility instrument; EQ-5D = European Quality of Life Questionnaire; HUI3 = Health Utilities Index; IVI = Impact of Vision Impairment; NEI VFQ-25 = National Eye Institute 25-item Visual Function Questionnaire; PROM = patient-reported outcome measure; RetCAT = Diabetic Retinopathy and Macular Edema Computerized Adaptive Testing System; RetDQoL = Diabetic Retinopathy Dependent Quality of Life; SF-6D = Short Form-6D; SG = standard gamble; TTO = time trade-off; VAS = visual analog scale; VisQoL = Vision and Quality of Life index.